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Pipeline

Our Pipeline

Our broad pipeline includes multiple targeted therapies that harness the immune system and target specific molecular pathways.

Global, excluding China, Hong Kong, and Macau

NDA

P.3

P.2

P.1

IND

Preclinic.

Discov.

Approved in China

Global Phase 2 SPARTA

Met Exon 14 NSCLC

APL-101 (Vebreltinib)

Global, excluding China, Hong Kong, and Macau

NDA

P.3

P.2

P.1

IND

Preclinic.

Discov.

Approved in China

Global Phase 2 SPARTA

Met amplified NSCLC

APL-101 (Vebreltinib)

Global, excluding China, Hong Kong, and Macau

NDA

P.3

P.2

P.1

IND

Preclinic.

Discov.

Approved in China

Global Phase 2 SPARTA

Met fusion GBM

APL-101 (Vebreltinib)

Global

NDA

P.3

P.2

P.1

IND

Preclinic.

Discov.

Solid tumors

APL-102

Global, excluding China

NDA

P.3

P.2

P.1

IND

Preclinic.

Discov.

Phase 1 Dose Escalation Study

Solid tumors

APL-501

Global, excluding China

NDA

P.3

P.2

P.1

IND

Preclinic.

Discov.

Approved in China

Ex-China in Development

Multiple tumor types

APL-502

Global

NDA

P.3

P.2

P.1

IND

Preclinic.

Discov.

Multiple tumor types

APL-801

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